肾移植病人群体反应性抗体的检测
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R699.2 R446.62

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Detection of panel reactive antibody in pre-transplantation patients
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    摘要:

    以36名健康成人外周血淋巴细胞作为群体淋巴细胞来源。采用补体依赖微量淋巴细胞毒方法,进行了55例肾移植病人的群体反应性抗体(panel reactive antibody,PRA)和随机淋巴细胞毒试验(random panel lymphocytotoxicity test,RPLT)的检测,结果显示,55例病人进行血清淋巴细胞毒交叉配合实验(CDC)检测,只有1例阳性(1.82%),而PRA及R

    Abstract:

    Thirty six healthy adults were included with their peripheral lymphocytes being collected as the panel lymphocytes,panel reactive antibody(PRA)and random panel lymphocytotoxicity test(RPLT)were conducted with micro?complement dependent cytotoxcity among 55 pre?transplantation patients,8 cases(14 5%)were shown positive in PRA,only 1 case(1 82%)was positive in the test of CDC.The results indicated:there were great differences between male and female( P <0 05),there was no obvious differentce between blood transfusion group and non?blood transfusion group( P >0 05),PRA was a more susceptible method than complement dependent cytotoxcity,there was perfect correlation between PRA and RPLT( r=0 95,P <0 001),RPLT is a simple and more reliable and more easily practised method to predict the sensitivity of recipients of renal transplantation.

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陈盛强 李留洋.肾移植病人群体反应性抗体的检测[J].临床检验杂志,2000,(4):207-209

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