Abstract:Objective:To study and analyze the platelet change trend, and clinical prognostic evaluation value of NPR and RPR in patients with severe burns. Methods:A total of 101 patients with burn area greater than 30% of the total surface area, admitted in our hospital from January 2017 to August 2019, were selected as the research objects. The time when the platelet count began to decrease after admission, the time when the platelet count reached the minimum value, the minimum value, the mean value, the area of the first eschar excision or shaving, and changes in platelet counts before and after surgery were recorded. On the 3rd day after the burn, a routine blood test was performed to detect the index values of the red blood cell average distribution width (RDW), neutrophil count (NEUT), and platelet count (PLT), and then the relevant values of RPR and NPR were calculated.Results:The Spearman rank correlation analysis revealed that the minimum platelet count value was positively correlated with the total burn area and burn area of Ⅲ degree. multiple linear regression analysis showed that the main influencing factors of plateletreduction were the larger burned area, the larger area of the eschar excision or shaving, blood transfusion, and unused growth hormone. Kaplan-Neier analysis showed that the values of RPR and NPR on the 3rd day after burn were correlated with patient survival rate.Conclusion:On the 3rd day after burn injury, RPR and NPR can be used as independent risk factors for predicting the prognosis and death of severely burned patients. The combination of two indicators to assess the survival and prognosis of patients after injury can further improve the evaluation accuracy.